Silymarin

Decades ago, a Company embarked on the journey to understand the twin benefits of a meaningful combination of medicine and nutrition. That Company - Alchem International Ltd which started making a significant impact years ago, has firmly arrived, with an array of nutraceutical products, duly acknowledged and widely accepted.

The processes, intensive research, planned investment, integrated capabilities, value additions through bio-technology, semi-synthesis, foot prints in the formulation space, directional progression and commitment to the cause has given the nutraceutical products of Alchem International Ltd deserved respect by the international community.

The production facilities have USFDA, EU GMP and WHO accreditations. Total commitment to quality drives the Company to its settled goals. Work towards growth resonates through the Company.

Alchem International with 75 years of experience in the phytochemical space has been diligently providing plant derived ingredients, active pharmaceutical ingredients and bulk drugs to all international significant geographies and the Company's interest in skin care is logical to its dimensional growth.

Sheer Quality drives Alchem’s operations

Through perfect blend of science and nature, dedicated research, selection of finest botanical herbal extracts and focused technology, Alchem has successfully extracted the potent active molecules in the plant and offers it for nutraceutical use to help various companies spread wellness.

Silymarin
"For nutraceutical use, Alchem offers Silymarin with all its inherent benefits"

Silybum marianum has other common names include cardus marianus, milk thistle, blessed milk thistle, Marian Thistle, Mary Thistle, Saint Mary's Thistle, Mediterranean milk thistle, variegated thistle and Scotch thistle. This species is an annual or biennial plant of the Asteraceae family. Originally a native of Southern Europe through to Asia, it is now found throughout the world. Milk thistle extract is composed of 65% to 80% silymarin. The remainder consists of polyphenolics and fatty acids, such as linoleic acid. Silymarin is a complex of at least 7 flavolignans, including silibinin, silychristin and silidianin and the flavonoid taxifolin. Silybin A and B, diastereoisomers of silibinin, are considered the most biologically active components, although isosilibinin may be more potent.

The flavonoid silymarin and one of its structural components, silibinin, are substances with documented hepatoprotective properties. Silymarin and silibinin act in four different ways: (i) as antioxidants, scavengers and regulators of the intracellular content of glutathione; (ii) as cell membrane stabilisers and permeability regulators that prevent hepatotoxic agents from entering hepatocytes; (iii) as promoters of ribosomal RNA synthesis, stimulating liver regeneration; and (iv) as inhibitors of the transformation of stellate hepatocytes into myofibroblasts, the process responsible for the deposition of collagen fibres leading to cirrhosis. The key mechanism that ensures hepatoprotection appears to be free radical scavenging. Moreover, anti-inflammatory and anti-carcinogenic properties have also been documented.

Silymarin is useful in liver care and is prescribed by herbalists to help treat liver diseases such as cirrhosis, jaundice and hepatitis.

The product addresses broad spectrum physiological concerns and has the band width and capabilities to meet expectations. Regular use should exhibit demonstrable results to inhibit various health related issues.

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