18 Beta Glycyrrhetinic Acid

Alchem International with 75 years of experience in the phytochemical space has been diligently providing plant derived ingredients, active pharmaceutical ingredients and bulk drugs to all international significant geographies.

The success of the company’s operations lie in its proprietary manufacturing processes, intensive research, willingness to combat new challenges, mesh with evolving technologies ,focussed expansion and credible response  to international validations and inspections.

The production sites are US FDA approved and WHO and EU GMP certified. The company has filed ASMF/DMFs in over 20 countries worldwide. Value additions through bio-technology, semi-synthesis and foot prints in the formulation space have happened in planned progression. Alchem’s interest in skin care is a logical part of this dimensional growth.

Sheer Quality drives Alchem’s operations

Through perfect blend of science and nature, dedicated research, selection of finest botanical herbal extracts and focused technology, Alchem has successfully extracted the potent active molecules in the plant and offers it for pharmaceutical use to help various companies spread wellness.

Glycyrrhetinic Acid
"For pharmaceutical use, Alchem offers Glycyrrhetinic Acid with all its inherent benefits"

Glycyrrhiza glabra, also known as licorice and sweetwood, is native to the Mediterranean and certain areas of Asia.  The primary antioxidant and anti-inflammatory compounds found in Licorice Root are the glycosides - glycyrrhizin and glycyrrizinic acid, flavonoids, and saponins. Glycyrrhizin, a triterpenoid compound, accounts for the sweet taste of licorice root. This compound represents a mixture of potassium-calcium-magnesium salts of glycyrrhizic acid that varies within a 2-25 percent range.

Glycyrrhetinic acid is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid. This molecule has been well known for centuries, in traditional medicine, for its anti-inflammatory efficacy.

As an anti-inflammatory agent, Glycyrrhetinic acid is believed to inhibit the enzymes that metabolize the prostaglandins, PGE2a to their inactive metabolites. This increases the level of prostaglandins in the digestive system. These prostaglandins inhibit gastric secretion but stimulate pancreatic secretion and mucous secretion in the intestines. This might be the reason that glycyrrhetinic acid is said to relieve peptic ulcers.

The product addresses broad spectrum physiological concerns and has the band width and capabilities to meet expectations. Regular use should exhibit demonstrable results to inhibit various health related issues.

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