Nicotine Polacrilex (EP/USP)Nicotine Resinate

Alchem International with 75 years of experience in the phytochemical space has been diligently providing plant derived ingredients, active pharmaceutical ingredients and bulk drugs to all international significant geographies.

The success of the company's operations lie in its proprietary manufacturing processes, intensive research, willingness to combat new challenges, mesh with evolving technologies ,focussed expansion and credible response to international validations and inspections.

The production sites are US FDA approved and WHO and EU GMP certified. The company has filed ASMF/DMFs in over 20 countries worldwide. Value additions through bio-technology, semi-synthesis and foot prints in the formulation space have happened in planned progression. Alchem's interest in skin care is a logical part of this dimensional growth.

Sheer Quality drives Alchem’s operations

Through perfect blend of science and nature, dedicated research, selection of finest botanical herbal extracts and focused technology, Alchem has successfully extracted the potent active molecules in the plant and offers it for pharmaceutical use to help various companies spread wellness.

Nicotine polacrilex/Nicotine resinate
"For pharmaceutical use, Alchem offers Nicotine polacrilex/Nicotine resinate with all its inherent benefits"

Nicotine polacrilex is the form of nicotine found in oral products used to help people quit smoking cigarettes. The nicotine is bound to an ion-exchange resin in these products to facilitate controlled release and aid in the absorption through the mucous membranes in the mouth. These products can provide a means to ease nicotine withdrawal symptoms and overcome the addiction to smoking.

Products containing nicotine polacrilex most often take the form of gum or occasionally lozenges. Nicotine polacrilex can help the person deal with withdrawal by providing a replacement source of nicotine without the other dangerous health effects of smoking. The Nicotine polacrilex gum provides a lower level of nicotine to the blood stream than cigarettes, prevents exposure to carcinogens, does not contain the tar or carbon monoxide of cigarette smoke and allows people to gradually reduce dependence on nicotine.

Nicotine Polacrilex chewing gum is formulated to provide blood nicotine levels via buccal absorption that approximates those produced by the inhalation of tobacco smoke. In this case, the pharmacokinetics of nicotine favors buccal (rather than gastrointestinal) absorption. Absorption from the mouth is more rapid than from the stomach and the absorbed nicotine avoids immediate and rapid inactivation by the liver.

The dosage of nicotine polacrilex varies for each individual, and generally depends on the extent of the person's smoking habit. There are most often two available dosages, one for light smokers who smoke less than 25 cigarettes per day and a higher dosage for heavier smokers. The product addresses broad spectrum physiological concerns and has the band width and capabilities to meet expectations. Regular use should exhibit demonstrable results to inhibit various health related issues.

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