Reserpine (CP)

Alchem International with 75 years of experience in the phytochemical space has been diligently providing plant derived ingredients, active pharmaceutical ingredients and bulk drugs to all international significant geographies.

The success of the company’s operations lie in its proprietary manufacturing processes, intensive research, willingness to combat new challenges, mesh with evolving technologies ,focussed expansion and credible response  to international validations and inspections.

The production sites are US FDA approved and WHO and EU GMP certified. The company has filed ASMF/DMFs in over 20 countries worldwide. Value additions through bio-technology, semi-synthesis and foot prints in the formulation space have happened in planned progression. Alchem’s interest in skin care is a logical part of this dimensional growth.

Sheer Quality drives Alchem’s operations

Through perfect blend of science and nature, dedicated research, selection of finest botanical herbal extracts and focused technology, Alchem has successfully extracted the potent active molecules in the plant and offers it for pharmaceutical use to help various companies spread wellness.

Reserpine
"For pharmaceutical use, Alchem offers Reserpine with all its inherent benefits"

Reserpine is an alkaloid isolated from the root of the snakeroot plant (Rauwolfia serpentina), a small evergreen climbing shrub of the dogbane family native to the Indian subcontinent. Known in India as Sarpaganda, it has been used for centuries to treat hypertension, insanity, snakebite, and cholera due to its antipsychotic and antihypertensive properties.

Reserpine irreversibly binds to the storage vesicles of neurotransmitters, particularly norepinephrine, serotonin and dopamine causing catecholamines to leak into the synapse so that they are not available for release when the pre-synaptic neuron is stimulated. Eventually, catecholamine depletion occurs because of the body's inability to store these neurotransmitters. The antihypertensive actions of reserpine are a result of its ability to deplete catecholamines from peripheral sympathetic nerve endings. These substances are normally involved in controlling heart rate, force of cardiac contraction and peripheral vascular resistance and thus, result in a reduction in both cardiac output and peripheral vascular resistance with long term therapy, which takes approximately 3 weeks to develop after the initiation of therapy. 

The chief use of reserpine is for treating mild essential hypertension. It is also useful as adjunctive therapy with other antihypertensive agents in the more severe forms of hypertension. It is used in cases of mild anxiety and to treat severe agitation in patients with mental disorders (e.g., schizophrenia), primarily in those individuals unable to tolerate phenothiazine derivatives or in those who also require antihypertensive medication.

The product addresses broad spectrum physiological concerns and has the band width and capabilities to meet expectations. Regular use should exhibit demonstrable results to inhibit various health related issues.

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